Acute generalized exanthematous pustulosis
Acute generalized exanthematous pustulosis (AGEP) rara est reactio cutis, quae in 90 % casuum ad administrationem medicamentorum referitur. Acute generalized exanthematous pustulosis characterizatur repentinis eruptionibus cutaneis, quae mediis quinque diebus post incipiendum medicamenti apparent. Haec eruptiones sunt pustulae, id est parvae, rubrae vel albae vel roseae eruptiones cutis, quae materialem serosum vel purulentum continent. Lesiones cutis plerumque intra 1‑3 dies se manifestant.
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In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
Latae laesiones cum erythemate et pusulis repente apparent.
relevance score : -100.0%
ReferencesAcute generalized exanthematous pustulosis (AGEP) est reactio cutis parva, cum pustulis repletis, quae in basi cutis rubra se manifestat. Saepe fit, cum quaedam medicamenta, ut antibiotica, sumuntur, et celeriter per corpus diffunditur. Cum medicamentum excitans cessat, signa typice intra duas septimanas evanescunt, saepe cum levata cutis effusione. Etsi plerumque non sunt graves et ad cutem limitatae, graves causas possunt celare, inter alias reactiones cutis graves, ut Stevens-Johnson syndrome vel toxic epidermal necrolysis. Curatio praecipua est suspendere medicamenta et praebere curam symptomatum, quae plerumque sufficit ad plenam resolutionem morbi.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Recent experimental data reviewed herein are supportive of an early role of drug-induced innate immune activation and innate cytokines such as interleukin (IL)-1, IL-36, and IL-17 in the pathogenesis of AGEP. This explains the rapid onset and neutrophilic character of the cutaneous inflammation.
Vir LXXVI annos natus ad tempus cubiculi venit quod pellis eius praeterito biduo mutaverat. Doctores inaequaliter rubra invenerunt et areas in stipite et brachiis et cruribus excitaverunt. Procedente tempore, hae inaequaliter conjunctae sunt, et pustulis sicut labefecit in locis rubris. Testi ostendit cellam sanguineam albam summam cum sortibus typum appellatum neutrophils, et gradus C-reactive protein auctus est.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
